An extensive review of research published in Environmental Health supports the growing evidence that synthetic food dyes, popular in processed foods and medications, may adversely affect children’s neurobehavioral health, particularly by enhancing symptoms of Attention Deficit/Hyperactivity Disorder (ADHD). 

Examining 27 clinical human trials, the California Office of Environmental Health Hazard Assessment (OEHHA) discovered that 64% showed links between synthetic dye exposure and behavioral changes, with 52% of these associations showing statistical significance. Further meta-analysis concluded that approximately 8% of children might see enhanced effects of their ADHD symptoms as a result of synthetic dye consumption. When looking at animal toxicology studies, researchers found behavioral and cognitive impairments when exposed to levels of synthetic dyes at the current FDA Acceptable Daily Intakes (ADIs) and even below them. These levels were established without fully considering neurobehavioral outcomes. Both Red No. 3 and Yellow No. 5 have been correlated with altered activity levels and disruptions in neurotransmitter systems, even when doses are ten times lower than the existing thresholds set by the FDA. 

These findings call attention to the substantial gaps in regulatory protections, especially concerning children who are more likely to consume synthetic dyes at higher relative doses. Based on this evidence, updated safety standards and reduced use of synthetic dyes in edible products are crucial for reducing neurodevelopmental risks. 

Organic agriculture provides a critical alternative by eliminating synthetic dyes altogether while promoting whole food ingredients that boost neurodevelopmental health and advance environmental sustainability. This research shows that when families make the choice to eat organic products, they likely reduce their exposure to harmful additives and, instead, are able to eat healthier while supporting environmentally friendly practices.